Healthcare portfolio management software that connects strategy to execution

OnePlan gives PMO, IT, and clinical operations leaders at hospitals, health systems, and payers one governed platform to plan, prioritize, and deliver the initiatives that improve care and protect margin — without adding another disconnected tool to the stack.

Trusted by PMO and IT leaders across health systems and payers

childrens healthcare atlanta
summa health
baptist logo
prime logo
novari logo
diversus logo

What is healthcare portfolio and project management software?

Healthcare portfolio and project management software is an enterprise platform that hospitals, health systems, payers, medical device manufacturers, and health IT organizations use to prioritize, fund, staff, and govern their strategic initiatives in one place. It differs from general task management tools by operating at the portfolio level: connecting board-approved strategy to delivery, modeling competing investments against real capacity and budget, and maintaining the auditable approval trail that HIPAA and regulatory readiness require.

OnePlan serves the care delivery and health services side of the industry — providers, payers, medical device, and health IT — rather than pharmaceutical drug development. Health systems typically adopt it to replace spreadsheets and disconnected trackers across the PMO, IT, and clinical operations.

Key Takeaways

Health systems use portfolio management software to connect strategy to execution across clinical, IT, and PMO teams.

Around 70% of hospitals report a failed AI pilot due to workflow misalignment; formal AI governance doubles the likelihood of hitting ROI.

The core capabilities to evaluate are portfolio prioritization, resource capacity planning, financial tracking, and audit-ready governance.

OnePlan is used by Children's Healthcare of Atlanta, Summa Health, Baptist Health Care, Prime Therapeutics, Novari Health, and Diversus Health.

Your strategy is sound. Execution is where it stalls.

Health systems are under more pressure than ever to modernize care delivery while governing AI responsibly — and most are doing it with tools that were never built for the job.

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Strategy-Execution Disconnect

Board-approved priorities are tracked in spreadsheets and status decks, so leadership can't see whether strategic initiatives are actually moving — or where they've stalled.

A recurring theme at this year's leading health IT conferences: organizations are moving beyond static reporting toward real execution visibility.

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AI Disruption of Decision-Making

AI is reshaping care delivery, operations, and strategic decision-making faster than most portfolios can plan around it, leaving leaders reacting instead of directing.

A focus area across major healthcare technology conferences this year, tracking AI's expanding role in care delivery and strategy.

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Speed of Governance

AI capabilities are advancing faster than governance frameworks, regulatory structures, and data infrastructure can keep up — creating exposure with every ungoverned pilot.

Widely discussed on healthcare technology conference stages this year: governance frameworks outpaced by AI capability.

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Resource & Capacity Reality

Roughly 70% of hospitals report a failed AI pilot due to workflow misalignment — and systems with a formal AI governance council are twice as likely to hit ROI.

Cited in industry research shared across healthcare technology conferences this year.

Better Decisions

Turning strategy into action with AI-informed, governed decision-making — balancing speed, certainty, and control.

Better Execution

Resource and capacity management, cross-functional alignment, and removing the bottlenecks that stall delivery.

Better Organizations

Governance and operating models that scale accountability instead of slowing everything down.

The industry is converging on the same shifts

Healthcare portfolio management conferences this year have organized their agendas around three themes that map directly to the four challenges above. OnePlan is part of that conversation alongside the rest of the PPM category.

Based on themes across major healthcare and life sciences PPM conferences in 2026

One governed platform for strategy, delivery, and oversight

OnePlan replaces the spreadsheets, disconnected trackers, and one-off AI pilots with a single system of record built for portfolio-level decisions.

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Strategy & Portfolio Alignment

Connect board-approved priorities to program and project execution with real-time roll-ups leadership can actually trust.

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AI Governance Workspace

Stand up AI governance councils, intake pilots, and track risk, workflow impact, and ROI in one governed system instead of scattered spreadsheets.

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Scenario Planning & Prioritization

Model competing initiatives against capacity, budget, and strategic value before committing resources — not after.

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Resource & Capacity Management

See real-time capacity across clinical informatics, IT, and PMO staff to catch overallocation before it derails a launch.

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Compliance-Ready Workflows

Structured approvals and audit trails built for HIPAA and regulatory readiness, so nothing depends on someone remembering an email thread.

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Executive Reporting

One dashboard that rolls up initiatives across service lines and systems, built for the questions your board actually asks.

One platform, tailored to how each team works

Whether you run an enterprise PMO, an IT portfolio, a clinical informatics program, or a transformation office, OnePlan gives your team the same governed source of truth.

Enterprise PMO Leaders

Prioritize and govern the full portfolio of strategic initiatives.

  • Standardize intake across departments
  • Standardize intake across departments
  • Standardize intake across departments

Director, PMO · Director, Enterprise PMO · Sr. Manager, Enterprise PMO · Manager / Senior Manager, PMO · Chief of Staff, Health System PMO

IT Portfolio & Governance Leaders

Deliver technology and digital health initiatives on time and in scope.

  • Track EHR, integration, and platform projects
  • Align IT capacity to demand
  • Reduce risk on vendor-dependent timelines

Director, IT PMO · VP, IT Program Management · Director, IT Portfolio & Governance · Director, IT Governance & Portfolio · Head of IT Project Delivery

Clinical & Operational Portfolio Leaders

Coordinate quality, safety, capital, and service-line initiatives across teams.

  • Connect clinical projects to outcomes
  • Manage cross-functional dependencies
  • Keep frontline initiatives visible to leadership

Director, Clinical Informatics Portfolio · Director, Digital Health Portfolio · VP, Operations & Portfolio Management · Director, Capital Projects & Portfolio · Director, Operational Excellence

Transformation & Strategic Initiative Leaders

See portfolio health and risk at a glance, without a status meeting.

  • Real-time view of strategic investments
  • Financial and resource exposure by initiative
  • Board-ready reporting on demand

VP, Digital Transformation · VP, Transformation & Innovation · Head of Transformation · Director, Business Transformation · Director, Change & Transformation  · Sr. Director, Enterprise Transformation · Director, Strategic Initiatives

Built for enterprise healthcare portfolios, not generic to-do lists

General work management tools help teams track tasks. Health systems need to govern strategy, capacity, spend, and risk at the portfolio level — that requires more depth.

Capability
Generic work management tools
OnePlan for healthcare
Portfolio-level prioritization
Native financial & resource management
Governance & audit trails
Cross-department capacity visibility
Scenario planning for competing initiatives
10 hrs → 2

weekly scheduling meetings cut after centralizing intake and resource approvals
Children's Healthcare of Atlanta

3

delivery methodologies — waterfall, agile, and Six Sigma — supported in one portfolio
Diversus Health

7,000+

employees supported across emergency, acute, outpatient, and long-term care
Summa Health

Why Users love OnePlan

Scott Martin
Chief Information Officer, Diversus Health

“Providing clarity is crucial, especially in a time of hybrid work where people can feel disconnected. We aim to establish a culture where everyone's work is valued and contributes to our success. OnePlan's SPM solution enables this sense of ownership and engagement.”

Rated 5 out of 5
SOL-Millennium
Global medical device manufacturer

“OnePlan offers limitless possibilities to align with our company's priorities.”

Rated 5 out of 5
FAQs

Frequently Asked Questions

What healthcare leaders ask before choosing a PPM platform

Look for a platform that connects board-approved strategy to day-to-day delivery, supports scenario planning and prioritization across service lines, gives real-time resource and capacity visibility across clinical, IT, and PMO staff, and maintains audit-ready governance for HIPAA and regulatory requirements. OnePlan was built for exactly this: enterprise-grade portfolio management purpose-built for the operating reality of health systems and payers.

A portfolio platform supports audit readiness by keeping intake, approvals, ownership, decisions, and changes in a governed system. OnePlan provides structured workflows and audit trails that help healthcare teams document oversight and prepare for regulatory reviews. The platform supports your organization’s governance processes; those processes and the way the system is configured remain essential.

Yes. OnePlan gives healthcare teams a governed workspace to intake AI pilots, assign ownership, review risk and workflow impact, and track expected value and ROI. An AI governance council can use the same portfolio view to prioritize pilots and monitor initiatives through delivery.

Task management tools focus on individual tasks and team execution. Enterprise PPM connects that work to strategic priorities, funding, resource capacity, and oversight across the organization. Health systems can compare competing investments and see how clinical, IT, and PMO initiatives affect the same portfolio.

OnePlan brings demand and available capacity into one portfolio view across clinical informatics, IT, and PMO staff. Leaders can identify overallocation, model competing initiatives, and align people and skills to the work the organization can realistically deliver.

See how OnePlan fits your health system

Talk to a team that understands healthcare portfolios — or see the platform in action with a guided demo.

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