Run your entire portfolio of assets, indications, programs, and products in one AI-enabled connected platform

From early research through commercial manufacturing and life cycle management, OnePlan connects every function, portfolio, and program. Align strategy with execution, optimize resources, make faster, data-driven decisions, and accelerate time to patient.

Built around Microsoft Project · No rip-and-replace

Trusted by Life Sciences Leaders Worldwide

Key Takeaways

One platform for assets, indications, and programs from discovery to commercial launch.

Manage by development stage or functional team — Research, CMC, Nonclinical, Clinical, Regulatory, Commercial.

Scenario planning ties timelines, resources, and financials to corporate & quarterly goals.

Built on Microsoft; connects to Teams, Project, Azure DevOps, Jira, Smartsheet and more.

What is life sciences PPM?

Life sciences project portfolio management (PPM) is the practice of planning, prioritizing, executing, and tracking a portfolio of assets, indications, and development programs across functional teams — from discovery through commercial launch. Instead of stitching together spreadsheets and disconnected tools, OnePlan brings all investments into a single hybrid PPM platform, so R&D, Commercial, Life Cycle Management, Product Supply, and IT teams can share a single source of truth and move confidently from strategy to execution.

life sciences ppm team collaboration

Eight ways OnePlan turns life sciences complexity into clarity

OnePlan connects R&D, Clinical, Regulatory, Manufacturing, and Commercial in one platform — replacing fragmented tools with the clarity, discipline, and transparency it takes to optimize time to patient.

Advisory Services

Strategize for Success

Single source of truth

Unify fragmented tools across every life sciences function—eliminating silos and duplicative reporting so leadership sees one consistent picture.

Objective portfolio prioritization

Allocate resources with a common scoring model linked to key results, focusing investment on the highest-value work—not the loudest voice.

Optimize

Resources & priorities

Strategy-to-execution linkage

Connect projects directly to goals and objectives, keeping work aligned from discovery through commercialization at every stage.

Governance clarity

Establish consistent roles, ownership, and accountability across complex programs, so every decision has a clear owner.

Mitigate

Risks proactively

Risk & delivery-health visibility

Consolidated, real-time views of risks, issues, and opportunities let leaders make proactive decisions before problems compound.

Executive reporting & decision support

Clear leadership dashboards enhance program visibility and enable data-driven, proactive decisions across the portfolio.

Accelerate

Innovation delivery

Portfolio & release transparency

Scalable views by status, project type, and milestone support balanced investment and clear management across the pipeline.

Execution discipline at scale

A consistent, scalable operating model lets teams efficiently manage growing programs while reducing friction and improving visibility.

Visualize all work

Bring siloed information together for full visibility into projects, products, and every other work item — with teams collaborating in one central location.

Control your investments

Prioritize the work that matters most and gain insight into current and future demand, so your resources stay focused on the initiatives with the biggest return.

Execute the way you work

Connect best-of-breed execution tools while giving teams the centralization they need to collaborate and make better decisions — in the tools they know best.

How OnePlan maps to each function
at every stage of development

Six problems every capital team knows too well.

1. Research / Discovery

Intake new assets and indications, score early candidates, and align discovery work to portfolio strategy.

2. CMC

Coordinate chemistry, manufacturing, and controls work with shared timelines, resources, and budgets.

3. Nonclinical

Track preclinical studies and dependencies, with visibility into how results shift downstream plans.

4. Clinical /
Discovery

Manage clinical studies as sub-plans, with capacity, cost, and schedule rolled up to the program.

5. Regulatory

Plan submissions as sub-plans and keep timelines, dependencies, and resourcing in lockstep.

6. Commercial

Drive launch readiness and beyond, connecting commercial work back to the same portfolio view.

Everything it takes to translate strategy into action

Plan, prioritize, resource, fund, and deliver the full life sciences portfolio in one connected platform.

Portfolio management & prioritization

Evaluate assets, indications, programs, and products against strategic goals, scientific value, risk, cost, and time to patient. Compare scenarios and make portfolio decisions with a consistent, transparent framework.

life sciences clinical development scenario comparison

Resource & capacity management

See current and future demand across functions, programs, and skills. Model trade-offs, resolve constraints, and direct scarce expertise to the work with the greatest impact.

Resource and capacity management dashboard

Financial management

Connect funding, forecasts, actuals, and lifecycle assumptions to portfolio decisions. Understand the financial impact of every scenario before commitments change.

Financial management dashboard
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Adaptive work management

Give teams the flexibility to manage stage-gate, waterfall, agile, or hybrid work while keeping milestones, dependencies, risks, and decisions connected to the portfolio.

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Reporting & analytics

Turn live portfolio, resource, financial, and execution data into role-based dashboards that help teams act and executives decide with confidence.

Real results: life sciences PPM with OnePlan

See how organizations use OnePlan to improve visibility, decisions, and delivery.

OnePlan vs. spreadsheets and point tools

Why life sciences PMOs move off disconnected spreadsheets and single-purpose tools.

Capability

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Spreadsheets & point tools

Cross-team portfolio visibility

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Siloed

Scenario planning & prioritization

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Manual

Resource capacity & trade-offs

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Limited

Lifecycle financial forecasting

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Disconnected

Connects to Microsoft, Jira, Smartsheet

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Rarely

OKR & corporate-goal alignment

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None

One-Stop-Shop for Success

From strategy and implementation through enablement and ongoing support, OnePlan helps teams realize value faster.

Advisory Services

Industry-leading consultants help you identify key goals and build a clear roadmap for success.

Implementation

Configurations tailored to your processes to maximize adoption and accelerate your transformation.

Training

OnePlan Academy — an adaptable, scalable learning platform for every learning style.

Product support

Expert guidance, adoption strategies, and dedicated consultants for ongoing optimization.

FAQs

Frequently Asked
Questions

Quick answers about life sciences PPM with OnePlan.

Life sciences PPM is the practice of planning, prioritizing, and tracking a portfolio of assets, indications, and development programs across functional teams — from discovery through commercial launch. OnePlan brings these investments together in one hybrid PPM platform so teams connect strategy to execution.

OnePlan connects portfolio strategy, programs, sub-plans, timelines, resources, risks, and financials in one place so biotech and pharmaceutical teams can manage work from discovery through commercialization.

Yes. OnePlan connects with Microsoft Teams, Project, Azure DevOps, Jira, Smartsheet, and other execution tools so teams can keep working in familiar systems while leadership gains one portfolio view.

OnePlan shows demand, availability, skills, and allocation across programs so leaders can identify constraints, compare trade-offs, and move resources to the highest-value work.

Yes. OnePlan is built on the Microsoft cloud and designed to extend Microsoft 365, Teams, Project, Power Platform, and Azure investments with connected strategic portfolio management.

Unlock success in every program

Bring your full life sciences portfolio together and accelerate strategy to execution. Sign up free today.

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